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Appearance:Solid
Throughput:100|Kilogram|Day
pd_productuse:intermediate
Delivery Time:in stock
Purity:98% purity
1-Acetyl-4-piperidinecarboxylic acid Chemical Properties
Melting point 180-184 °C (lit.)
Boiling point 301.17°C (rough estimate)
density 1.1998 (rough estimate)
refractive index 1.4750 (estimate)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
pka 4.35±0.20(Predicted)
color White to beige
Water Solubility 50 g/L (20 ºC)
BRN 389577
CAS DataBase Reference 25503-90-6(CAS DataBase Reference)
NIST Chemistry Reference 1-Acetyl-4-piperidinecarboxylic acid(25503-90-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-43
Safety Statements 26-36-37/39
WGK Germany 2
Hazard Note Irritant
HazardClass IRRITANT
HS Code 29339900
MSDS Information
Provider Language
1-Acetylpiperidine-4-carboxylic acid English
SigmaAldrich English
ACROS English
ALFA English
1-Acetyl-4-piperidinecarboxylic acid Usage And Synthesis
Chemical Properties White Crystalline Solid
Uses A synthetic intermediate in the preparation of CNS depressants
Uses Reactant for synthesis of:• ;Triazole derivatives1• ;Antiproliferative agents2• ;CDK inhibitors3• ;CCR5 antagonists for HIV treatment4• ;nhNK1 antagonists5• ;Piperidine derivatives6
Uses Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene.
1-Acetyl-4-piperidinecarboxylic acid Preparation Products And Raw materials
Raw materials Acetic anhydride-->Isopropyl alcohol-->Isopropyl ether-->Isonipecotic acid
Preparation Products 1-[4-(2,4-DIFLUORO-BENZOYL)-PIPERIDIN-1-YL]-ETHANONE-->4-BENZOYLPIPERIDINE HYDROCHLORIDE-->4-BENZOYLPIPERIDINE HYDROCHLORIDE
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